In 1971, H.H. The Aga Khan selected Mozhan Khadem as Design Consultant for the Aga Khan University in Karachi. In this capacity, Mozhan Khadem conceptualized the University and hospital as “the architecture of continuous interior spaces that surrounds the observer”–a tradition of Indo-Persian and Moghul architectural heritage of Pakistan. The plan contains a progression of sequential and unfolding landscaped courtyards, open spaces, entrance portals, fountains, and water features. In this respect, he also influenced the design of the volumetric weave of solids (buildings) and voids (open spaces), as well as the interior design of the facility.